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In a study of more than 100,000 people, researchers found
that those with less healthy lifestyles were more likely to reduce
their risk of colorectal cancer with regular aspirin use than those
with healthier behaviors (JAMA Oncol 2024 Aug 1). Regular
aspirin use was defined as two or more 325 mg tablets
a week or a daily 81 mg dose; less healthy lifestyles were
characterized by higher body mass index, smoking, greater
alcohol consumption, less physical activity, and poorer diet.
Those with the unhealthiest lifestyles had a 3.4% chance
of developing colorectal cancer if they didn’t take aspirin
regularly, whereas those who did had a 2.1% chance of
developing the disease. In contrast, people with the healthiest
lifestyles had a 1.5% chance of developing colorectal cancer
if they took aspirin regularly and a 1.6% chance if they didn’t.
This result suggests that physicians can pursue a nuanced
approach when prescribing aspirin for disease prevention.
(https://aacrjournals.org. 26 de julho a 01 de agosto 2024. Adaptado)